# Astrocytes with CD40 and MHC-II present antigens to drive CNS autoimmunity

Researchers identified a subset of astrocytes expressing CD40 and MHC-II that can act as antigen-presenting cells. These cells promote autoimmune responses in the central nervous system, offering a potential new target for treating diseases like multiple sclerosis.

**Importance:** 3/5

## Sources

### Science
- [Nature](https://www.nature.com/articles/s41586-026-10860-6) — 2026-08-05