# Study reveals molecular glue degrader switched on by glutathionylation

Researchers identified a novel molecular glue degrader that relies on the protein DCAF11 and becomes active through glutathionylation, a cellular modification. This discovery expands how targeted protein degradation can be controlled, potentially paving the way for new therapeutic approaches against disease-causing proteins.

**Importance:** 3/5

## Sources

### Science
- [Nature](https://www.nature.com/articles/s41586-026-10873-1) — 2026-08-05